D-Dimer-

D-Dimer D-dimer containing moieties are formed by plasmin degradation of factor XIIIa cross linked fibrin. Elevated levels of D-dimer are found in clinical conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE) and disseminated intravascular coagulation (DIC). Ddimer levels rise during pregnancy and high levels are associated with complications.