17α-Hydroxyprogesterone (17α-OHP) ELISA kit - Diagnostics Biochem Canada Inc.

17α-Hydroxyprogesterone (17α-OHP) ELISA kit Home/Our Products/ELISA kits/17α-Hydroxyprogesterone (17α-OHP) ELISA kit vial Reference: CAN-P-320 Kit Type: Competitive ELISA Kit Size: 96-well break-apart microplate Sensitivity: 0.11 ng/mL Sample Type: Human serum / 50 μL Calibrator Range: 0.15–20 ng/mL Total Assay Time: 75 minutes Download ▼ IFU English Note: When using the kit, the IFU version that is provided with the kit must be followed. CAN: EU: USA: Medical applications: Endocrinology Fertility 17α-Hydroxyprogesterone (17α-OHP) The steroid 17α-hydroxyprogesterone is produced by the adrenal cortex and gonads. 17α-OHP has little progestational activity, but it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Cpd-S is produced by the 21-hydroxylation of 17α-OHP. Measurement of 17α-OHP is a useful indirect indicator of 21-hydroxlase activity. In congenital 21-hydroxylase defi ciency, the most common variety of congenital adrenal hyperplasia (CAH), 17α-OHP is secreted in abundant excess. Measurement of 17α-OHP is therefore valuable in the initial diagnosis of CAH.